5F-AKB48 (also known as 5F-APINACA and AKB-48F) is a synthetic cannabinoid substance of the indazolecarboxamide class. It acts as a potent agonist for the CB1 and CB2 cannabinoid receptors
5F-AKB48 has been investigated in the scientific literature. It was first identified in South Korea and is available for sale as a grey area research chemical through online vendors.
Chemical Properties of 5F-AKB48
5F-AKB48, or N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide, is a synthetic indazolecarboxamide as it contains a substituted indazole group. This indazole moeity is substituted at R1 with a fluoropentyl chain, a substitution shared with 5F-PB-22. Additionally, the indazole is substituted at R3 with a carboxamide group. This carboxamide group is N-substituted at its terminal amine group with an adamantane group. This group consists of four fused cyclohexane rings in a unique structure called a diamondoid. 5F-AKB48 is an analog of STS-135 in which the core indole structure is substituted with an indazole base.
|Common names||STS-135 (5F-APICA)|
SubjectiveSide effects AKB-48F
Cannabinoids are commonly smoked or vaporized to achieve a quick onset of effects and rapid offset. 5F-AKB48 is orally active when dissolved in a lipid, which can increase the duration significantly. Like other cannabinoids, it is insoluble in water but dissolves in ethanol and lipids.
Physical side effects 5F-AKB48
- Motor control loss
- Appetite enhancement
- Pain relief
- Changes in gravity
Cognitive Side effects 5F-APINACA
- Emotion enhancement
- Thought connectivity
- Thought deceleration
- Conceptual thinking
- Analysis suppression
- Dream suppression
Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of also them).
- Amphetamines –
- Czech Republic
- United Kingdom
- United States
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