What is 5-MeO-MiPT?
5-Methoxy-N-methyl-N-isopropyltryptamine (also known as 5-MeO-MiPT and Moxy) is a psychedelic substance of the tryptamine class. It has become increasingly popular in recent years for its tactile effects that serve to enhance libido and sexual pleasure.
5-MeO-MiPT is chemically related to tryptamines like 5-MeO-DMT and 5-MeO-DiPT. It produces its psychoactive effects through activity at serotonin receptors in the brain.
The synthesis and pharmacology of 5-MeO-MiPT was first reported in 1985 by David Repke and Alexander Shulgin. Its effects in humans was documented in Shulgin’s book TiHKAL (“Tryptamines I Have Known and Loved”).
Chemical Properties of 5-MeO-MiPT
5-MeO-MiPT is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 5-MeO-MiPT is substituted at R5 of its indole heterocycle with a methoxy (MeO) functional group CH3O−; it also contains a methyl group and an isopropyl chain bound to the terminal amine RN of its tryptamine backbone (MiPT).
What are the Effects of 5-MeO-MiPT?
5-MeO-MiPT’s psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a [[Agonist#Agonists|partial agonist] and additional mechanisms of action such as the inhibition of MAO (i.e. digestive enzymes in the stomach) have also been speculated upon, though this has yet to be demonstrated scientifically. 5-MeO-MiPT Powder
Some of the most commonly reported effects of 5-MeO-MiPT are:
- Stimulation
- Increased libido
- Heightened tactile sensations
- Colour enhancement
- Pattern recognition enhancement
- Depersonalization
- Spontaneous bodily sensations
Some potential Side Effects of 5-MeO-MiPT:
- Nausea
- Vasoconstriction
- Increased heart rate
- Abnormal heartbeat
- Headaches
- Dehydration
- Bodily pressures
Legality
Where is 5-MeO-MiPT Illegal?
- Brazil
- Germany
- Japan
- United Kingdom
- Latvia
- Switzerland
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